Motif ID: TLX1..3_NFIC{dimer}.p2

Z-value: 3.538


Transcription factors associated with TLX1..3_NFIC{dimer}.p2:

Gene SymbolEntrez IDGene Name
Tlx1 21908 T-cell leukemia, homeobox 1
Tlx3 27140 T-cell leukemia, homeobox 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tlx3chr11_-_33103458-0.082.9e-01Click!
Tlx1chr19_+_45225176-0.045.6e-01Click!


Activity profile for motif TLX1..3_NFIC{dimer}.p2.

activity profile for motif TLX1..3_NFIC{dimer}.p2


Sorted Z-values histogram for motif TLX1..3_NFIC{dimer}.p2

Sorted Z-values for motif TLX1..3_NFIC{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX1..3_NFIC{dimer}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_55223449 102.320 Sparc
secreted acidic cysteine rich glycoprotein
chr18_-_33623069 87.230 NM_001109990
D0H4S114
DNA segment, human D4S114
chr14_+_102237708 75.775 Lmo7
LIM domain only 7
chr18_-_33623668 75.088 NM_001109988
D0H4S114
DNA segment, human D4S114
chr6_+_17256383 66.222 Cav1
caveolin 1, caveolae protein
chr18_-_33623287 66.192 NM_053078
D0H4S114
DNA segment, human D4S114
chr18_-_33623400 65.714 NM_001109989
D0H4S114
DNA segment, human D4S114
chr6_+_17256415 65.080 Cav1
caveolin 1, caveolae protein
chr6_+_17256369 64.906 NM_007616
Cav1
caveolin 1, caveolae protein
chr19_+_29999596 58.320 NM_133775
Il33
interleukin 33
chr1_+_51345952 55.084 NM_138741
Sdpr
serum deprivation response
chr3_+_90341208 51.572 S100a16
S100 calcium binding protein A16
chr8_-_87323896 50.963 Nfix
nuclear factor I/X
chr2_-_25325196 50.935 Ptgds
prostaglandin D2 synthase (brain)
chr1_+_51346086 50.927 Sdpr
serum deprivation response
chr5_-_116872852 50.512 NM_030704
Hspb8
heat shock protein 8
chr11_-_116515602 49.383 NM_030206
Cygb
cytoglobin
chr1_-_89470442 48.599 NM_001111314
Ngef
neuronal guanine nucleotide exchange factor
chr4_-_115320309 48.141 NM_007823
Cyp4b1
cytochrome P450, family 4, subfamily b, polypeptide 1
chr1_+_51346108 47.129 Sdpr
serum deprivation response
chr7_-_133819870 45.381 NM_133670
Sult1a1
sulfotransferase family 1A, phenol-preferring, member 1
chr15_-_78034648 44.803 Pvalb
parvalbumin
chr2_-_25325248 44.702 NM_008963
Ptgds
prostaglandin D2 synthase (brain)
chr5_+_136363769 44.579 NM_013560
Hspb1
heat shock protein 1
chr18_+_82723920 44.575 Mbp
myelin basic protein
chr16_+_96422243 44.439 Sh3bgr
SH3-binding domain glutamic acid-rich protein
chr18_+_82723854 44.159 NM_001025251
NM_001025255
NM_001025256
NM_001025258
NM_001025259
NM_001025254
Mbp





myelin basic protein





chr18_+_82723907 43.535 Mbp
myelin basic protein
chr11_-_116515361 43.187 Cygb
cytoglobin
chr15_-_78034565 42.813 NM_013645
Pvalb
parvalbumin
chr10_-_127058163 42.667 Lrp1
low density lipoprotein receptor-related protein 1
chr11_-_118216819 42.036 Timp2
tissue inhibitor of metalloproteinase 2
chr11_-_118216625 40.118 Timp2
tissue inhibitor of metalloproteinase 2
chr3_-_10208575 39.103 NM_024406
Fabp4
fatty acid binding protein 4, adipocyte
chr11_-_118216689 38.724 NM_011594
Timp2
tissue inhibitor of metalloproteinase 2
chr2_+_32483909 38.310 NM_001198792
Ak1
adenylate kinase 1
chrX_+_162676903 38.208 Gpm6b
glycoprotein m6b
chr7_+_35971403 37.546 NM_017394
Slc7a10
solute carrier family 7 (cationic amino acid transporter, y+ system), member 10
chr11_-_118216591 36.704 Timp2
tissue inhibitor of metalloproteinase 2
chr5_+_136363810 36.277 Hspb1
heat shock protein 1
chr2_-_168559743 36.105 Atp9a
ATPase, class II, type 9A
chr5_+_136363914 35.784 Hspb1
heat shock protein 1
chr1_+_74379182 34.647 NM_019999
Pnkd
paroxysmal nonkinesiogenic dyskinesia
chr3_+_94736993 34.501 NM_009150
Selenbp1
selenium binding protein 1
chr9_-_56008770 34.374 Tspan3
tetraspanin 3
chr8_+_23868194 34.252 NM_008872
Plat
plasminogen activator, tissue
chr16_-_85803359 33.897 NM_009621
Adamts1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
chr1_-_72921438 33.539 NM_010518
Igfbp5
insulin-like growth factor binding protein 5
chr9_-_56008819 33.158 Tspan3
tetraspanin 3
chr5_-_5514787 32.509 NM_001193660
NM_001193659
NM_001193661
NM_022890
Cldn12



claudin 12



chr3_-_8666930 32.079 Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr3_+_94736974 32.062 Selenbp1
selenium binding protein 1
chr14_-_9142289 31.962 NM_183187
Fam107a
family with sequence similarity 107, member A
chr9_-_56008595 31.068 Tspan3
tetraspanin 3
chr9_-_56008828 29.945 NM_019793
Tspan3
tetraspanin 3
chr11_-_109957250 29.701 NM_153145
Abca8a
ATP-binding cassette, sub-family A (ABC1), member 8a
chr17_-_56249206 29.544 NM_020568
Plin4
perilipin 4
chr5_-_5514729 29.310 Cldn12
claudin 12
chr7_-_31839825 29.206 NM_052991
NM_194321
Fxyd1

FXYD domain-containing ion transport regulator 1

chr11_+_78137699 29.165 NM_009657
Aldoc
aldolase C, fructose-bisphosphate
chr2_+_20211539 28.884 NM_001081006
Etl4
enhancer trap locus 4
chrX_+_20265093 28.821 Cdk16
cyclin-dependent kinase 16
chr1_-_79436564 28.694 NM_009129
Scg2
secretogranin II
chr16_-_85803343 28.092 Adamts1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
chr15_-_75921924 27.869 Nrbp2
nuclear receptor binding protein 2
chr7_-_126138689 27.564 NM_001195774
NM_022420
Gprc5b

G protein-coupled receptor, family C, group 5, member B

chr5_-_77544147 27.473 NM_175606
Hopx
HOP homeobox
chr1_+_196765014 27.163 NM_001111059
NM_133654
Cd34

CD34 antigen

chr2_-_113878535 26.773 NM_009608
Actc1
actin, alpha, cardiac muscle 1
chr6_-_115201866 25.956 NM_080639
Timp4
tissue inhibitor of metalloproteinase 4
chr12_+_30687597 25.598 Pxdn
peroxidasin homolog (Drosophila)
chr1_-_72921098 25.440 Igfbp5
insulin-like growth factor binding protein 5
chr7_-_104566013 25.118 NM_009381
Thrsp
thyroid hormone responsive SPOT14 homolog (Rattus)
chr6_+_90424727 24.951 Klf15
Kruppel-like factor 15
chr17_+_6106829 24.811 NM_001103181
Tulp4
tubby like protein 4
chr2_+_35122282 24.439 Gsn
gelsolin
chr1_+_196765079 24.405 Cd34
CD34 antigen
chr3_-_8666985 24.267 Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr15_+_81633192 23.646 Tef
thyrotroph embryonic factor
chr10_-_126978704 23.279 Lrp1
low density lipoprotein receptor-related protein 1
chrX_+_20265584 22.996 Cdk16
cyclin-dependent kinase 16
chr6_-_115201846 22.833 Timp4
tissue inhibitor of metalloproteinase 4
chr19_+_5741862 22.759 Ltbp3
latent transforming growth factor beta binding protein 3
chr17_-_34960292 22.728 NM_011413
C4a
complement component 4A (Rodgers blood group)
chr15_+_75427044 22.077 NM_026730
Gpihbp1
GPI-anchored HDL-binding protein 1
chr19_+_29999624 22.037 Il33
interleukin 33
chr8_-_126418628 22.007 NM_009606
Acta1
actin, alpha 1, skeletal muscle
chrX_-_49967112 21.992 NM_016697
Gpc3
glypican 3
chr2_+_32502107 21.886 NM_001146348
NM_001146350
NM_007932
Eng


endoglin


chr7_-_51780003 21.816 NM_146189
Mybpc2
myosin binding protein C, fast-type
chr3_-_129458190 21.699 NM_010113
Egf
epidermal growth factor
chr9_+_43915391 21.684 NM_001190319
C1qtnf5
C1q and tumor necrosis factor related protein 5
chr4_-_142889372 21.525 NM_010329
Pdpn
podoplanin
chr4_-_129852325 21.440 NM_023476
Tinagl1
tubulointerstitial nephritis antigen-like 1
chr16_+_96422285 21.267 Sh3bgr
SH3-binding domain glutamic acid-rich protein
chr8_+_97296066 21.183 NM_009142
Cx3cl1
chemokine (C-X3-C motif) ligand 1
chr5_-_77543903 21.138 Hopx
HOP homeobox
chr7_-_112630662 20.867 NM_028444
Prkcdbp
protein kinase C, delta binding protein
chr14_-_35187767 20.718 NM_011430
Sncg
synuclein, gamma
chr9_+_43915327 20.690 NM_001040631
NM_001040632
C1qtnf5

C1q and tumor necrosis factor related protein 5

chr18_-_64820573 20.532 NM_001001488
Atp8b1
ATPase, class I, type 8B, member 1
chr2_+_172978566 20.384 NM_011044
Pck1
phosphoenolpyruvate carboxykinase 1, cytosolic
chr3_-_88297220 20.284 NM_019390
Lmna
lamin A
chrX_-_49967090 20.175 Gpc3
glypican 3
chr6_+_135313010 20.152 Emp1
epithelial membrane protein 1
chr13_-_3917356 19.868 NM_019671
Net1
neuroepithelial cell transforming gene 1
chr7_-_126138646 19.740 Gprc5b
G protein-coupled receptor, family C, group 5, member B
chr3_+_94497485 19.688 NM_019414
Selenbp2
selenium binding protein 2
chr1_+_196765124 19.506 Cd34
CD34 antigen
chr1_-_174136874 19.371 NM_011063
Pea15a
phosphoprotein enriched in astrocytes 15A
chr4_+_94405963 19.333 NM_013690
Tek
endothelial-specific receptor tyrosine kinase
chr7_+_52105323 19.244 Akt1s1
AKT1 substrate 1 (proline-rich)
chr7_+_52104591 18.992 NM_026270
Akt1s1
AKT1 substrate 1 (proline-rich)
chr7_+_28914482 18.975 NM_001164655
9530053A07Rik
RIKEN cDNA 9530053A07 gene
chr3_-_8667013 18.766 NM_010423
Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr2_+_84890611 18.739 NM_001081260
Tnks1bp1
tankyrase 1 binding protein 1
chr8_-_70342105 18.631 NM_027626
Psd3
pleckstrin and Sec7 domain containing 3
chr5_+_111847185 18.560 NM_001081235
Mn1
meningioma 1
chr11_+_32196488 18.536 NM_001083955
NM_008218
Hba-a2
Hba-a1
hemoglobin alpha, adult chain 2
hemoglobin alpha, adult chain 1
chr2_-_170232008 18.513 Bcas1
breast carcinoma amplified sequence 1
chr11_-_75236085 18.466 NM_011340
Serpinf1
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr19_-_5924796 18.429 Cdc42ep2
CDC42 effector protein (Rho GTPase binding) 2
chrX_-_45388010 18.250 NM_013912
Apln
apelin
chr16_+_96422076 18.035 NM_015825
Sh3bgr
SH3-binding domain glutamic acid-rich protein
chr4_-_91038729 17.972 NM_010486
NM_207686
Elavl2

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)

chr3_-_107734481 17.856 NM_026672
Gstm7
glutathione S-transferase, mu 7
chr2_+_32502186 17.811 Eng
endoglin
chr7_-_26180629 17.796 Lipe
lipase, hormone sensitive
chr12_+_96930429 17.779 NM_201518
Flrt2
fibronectin leucine rich transmembrane protein 2
chr13_+_38436987 17.639 Bmp6
bone morphogenetic protein 6
chr2_-_115890747 17.231 NM_001136072
NM_001159567
NM_001159568
NM_010825
Meis2



Meis homeobox 2



chr3_-_83967952 17.226 Trim2
tripartite motif-containing 2
chr10_+_115738429 17.207 NM_029928
Ptprb
protein tyrosine phosphatase, receptor type, B
chr13_-_69138164 17.101 Adcy2
adenylate cyclase 2
chr6_+_135312948 17.072 NM_010128
Emp1
epithelial membrane protein 1
chr15_+_81633102 16.779 NM_153484
Tef
thyrotroph embryonic factor
chr4_-_150482562 16.543 Camta1
calmodulin binding transcription activator 1
chr17_-_56261311 16.425 NM_029796
Lrg1
leucine-rich alpha-2-glycoprotein 1
chr1_-_174136809 16.057 Pea15a
phosphoprotein enriched in astrocytes 15A
chr5_+_21049296 16.043 NM_028977
Lrrc17
leucine rich repeat containing 17
chr6_+_17231334 15.988 NM_016900
Cav2
caveolin 2
chr14_+_121434765 15.877 NM_134082
Farp1
FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
chr7_+_147960463 15.794 Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
chr6_-_55124983 15.742 NM_009349
Inmt
indolethylamine N-methyltransferase
chr2_-_25978328 15.281 NM_026495
Nacc2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr1_+_132723258 15.229 NM_011082
Pigr
polymeric immunoglobulin receptor
chr11_+_78136681 15.206 Aldoc
aldolase C, fructose-bisphosphate
chr7_+_138175581 15.089 NM_007769
Dmbt1
deleted in malignant brain tumors 1
chr16_-_84835213 15.010 Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr4_+_62360705 14.927 Rgs3
regulator of G-protein signaling 3
chr13_+_49639799 14.870 NM_001172481
NM_025711
Aspn

asporin

chr19_+_32694494 14.787 NM_011864
Papss2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr11_-_101026399 14.648 Plekhh3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr7_-_108025317 14.647 Arhgef17
Rho guanine nucleotide exchange factor (GEF) 17
chr4_-_57929087 14.594 NM_178727
D630039A03Rik
RIKEN cDNA D630039A03 gene
chr16_-_18426802 14.567 NM_001111062
NM_007744
Comt

catechol-O-methyltransferase

chr7_-_20355818 14.564 Bcam
basal cell adhesion molecule
chr7_-_28118628 14.543 NM_001113549
Ltbp4
latent transforming growth factor beta binding protein 4
chr11_+_28753190 14.485 NM_146015
Efemp1
epidermal growth factor-containing fibulin-like extracellular matrix protein 1
chr2_+_106533615 14.331 NM_001143683
Mpped2
metallophosphoesterase domain containing 2
chr15_+_54577256 14.196 NM_010930
Nov
nephroblastoma overexpressed gene
chr2_+_106533281 14.193 Mpped2
metallophosphoesterase domain containing 2
chr6_-_115201790 13.895 Timp4
tissue inhibitor of metalloproteinase 4
chr11_-_75236012 13.817 Serpinf1
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr10_+_57504720 13.742 NM_021272
Fabp7
fatty acid binding protein 7, brain
chr7_+_138079669 13.703 NM_019564
Htra1
HtrA serine peptidase 1
chr8_-_49760037 13.687 NM_001145937
NM_011857
Odz3

odd Oz/ten-m homolog 3 (Drosophila)

chr8_+_91115856 13.595 Nkd1
naked cuticle 1 homolog (Drosophila)
chr8_-_37796104 13.359 NM_001194941
Dlc1
deleted in liver cancer 1
chr1_+_132723277 13.281 Pigr
polymeric immunoglobulin receptor
chr1_+_43787692 13.141 1500015O10Rik
RIKEN cDNA 1500015O10 gene
chr2_+_25145414 13.127 NM_146117
Lrrc26
leucine rich repeat containing 26
chr6_+_17231172 13.127 Cav2
caveolin 2
chr16_-_18426446 13.050 Comt
catechol-O-methyltransferase
chr6_+_54631644 13.017 NM_026629
2410066E13Rik
RIKEN cDNA 2410066E13 gene
chrX_+_162676870 13.012 NM_001177961
NM_001177962
NM_023122
Gpm6b


glycoprotein m6b


chr3_-_85550130 13.012 NM_172682
Fam160a1
family with sequence similarity 160, member A1
chr3_+_87834761 12.914


chr6_-_23082901 12.788 NM_013930
Aass
aminoadipate-semialdehyde synthase
chr9_-_77956353 12.616 NM_023605
Fbxo9
f-box protein 9
chr11_-_101026888 12.588 Plekhh3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr2_+_149656518 12.559 NM_001085521
Tmem90b
transmembrane protein 90B
chr14_+_8835385 12.512 NM_025341
Abhd6
abhydrolase domain containing 6
chr11_-_88712812 12.507 NM_009648
Akap1
A kinase (PRKA) anchor protein 1
chr14_-_55734213 12.378 NM_001003829
Jph4
junctophilin 4
chr7_-_151621960 12.344 Cttn
cortactin
chrX_+_148613496 12.156 NM_001005475
Iqsec2
IQ motif and Sec7 domain 2
chr10_-_88720534 12.128 NM_178773
Ano4
anoctamin 4
chr9_-_42924626 12.067 NM_001034863
Tmem136
transmembrane protein 136
chr1_+_137665517 12.002 Phlda3
pleckstrin homology-like domain, family A, member 3
chr11_+_78136690 11.982 Aldoc
aldolase C, fructose-bisphosphate
chr1_-_72920776 11.962 Igfbp5
insulin-like growth factor binding protein 5
chr10_-_127058199 11.879 NM_008512
Lrp1
low density lipoprotein receptor-related protein 1
chr17_-_87665228 11.874 NM_139295
NM_176808
Mcfd2

multiple coagulation factor deficiency 2

chr1_+_135142673 11.842 NM_001160268
NM_182930
Plekha6

pleckstrin homology domain containing, family A member 6

chr3_+_96405063 11.826 Lix1l
Lix1-like
chr8_+_97296110 11.726 Cx3cl1
chemokine (C-X3-C motif) ligand 1
chr3_+_90330770 11.488 NM_001163525
NM_001163526
NM_025393
S100a14


S100 calcium binding protein A14


chr12_+_36719492 11.452 NM_011783
Agr2
anterior gradient 2 (Xenopus laevis)
chr13_-_69138229 11.407 Adcy2
adenylate cyclase 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.66 2.53e-09 GO:0032502 developmental process
1.76 2.01e-08 GO:0048731 system development
1.70 3.36e-08 GO:0048856 anatomical structure development
1.65 8.30e-08 GO:0007275 multicellular organismal development
1.54 1.26e-05 GO:0051179 localization
2.03 3.41e-05 GO:0032879 regulation of localization
3.00 6.23e-05 GO:0032787 monocarboxylic acid metabolic process
1.81 9.73e-05 GO:0023051 regulation of signaling
2.29 1.15e-04 GO:0042180 cellular ketone metabolic process
2.31 1.31e-04 GO:0019752 carboxylic acid metabolic process
2.31 1.31e-04 GO:0043436 oxoacid metabolic process
1.90 1.35e-04 GO:0007399 nervous system development
2.57 1.38e-04 GO:0044283 small molecule biosynthetic process
2.25 2.65e-04 GO:0006082 organic acid metabolic process
3.35 4.21e-04 GO:0016053 organic acid biosynthetic process
3.35 4.21e-04 GO:0046394 carboxylic acid biosynthetic process
3.17 7.12e-04 GO:0006631 fatty acid metabolic process
1.53 1.31e-03 GO:0048522 positive regulation of cellular process
1.68 1.58e-03 GO:0044281 small molecule metabolic process
1.49 2.04e-03 GO:0051234 establishment of localization
1.48 2.21e-03 GO:0048518 positive regulation of biological process
1.58 3.19e-03 GO:0048869 cellular developmental process
1.97 3.21e-03 GO:0051128 regulation of cellular component organization
1.78 3.65e-03 GO:0009966 regulation of signal transduction
3.85 3.68e-03 GO:0030324 lung development
3.79 4.59e-03 GO:0030323 respiratory tube development
7.13 5.71e-03 GO:0046324 regulation of glucose import
1.81 6.00e-03 GO:0010646 regulation of cell communication
1.47 6.31e-03 GO:0006810 transport
2.58 6.40e-03 GO:0035295 tube development
1.56 7.66e-03 GO:0030154 cell differentiation
1.66 8.72e-03 GO:0051239 regulation of multicellular organismal process
2.11 8.92e-03 GO:0044255 cellular lipid metabolic process
1.63 9.01e-03 GO:0048583 regulation of response to stimulus
2.19 1.03e-02 GO:0072358 cardiovascular system development
2.19 1.03e-02 GO:0072359 circulatory system development
3.38 1.23e-02 GO:0019216 regulation of lipid metabolic process
1.49 1.30e-02 GO:0048519 negative regulation of biological process
2.83 1.44e-02 GO:0030029 actin filament-based process
3.19 1.61e-02 GO:0042391 regulation of membrane potential
6.26 1.82e-02 GO:0010827 regulation of glucose transport
1.93 2.06e-02 GO:0051049 regulation of transport
3.39 2.09e-02 GO:0060541 respiratory system development
3.91 2.39e-02 GO:0006633 fatty acid biosynthetic process
2.44 3.58e-02 GO:0040012 regulation of locomotion
4.68 3.65e-02 GO:0048771 tissue remodeling
1.54 3.84e-02 GO:0065008 regulation of biological quality
2.43 4.00e-02 GO:0001944 vasculature development
1.85 4.26e-02 GO:0006629 lipid metabolic process
7.67 4.33e-02 GO:0046326 positive regulation of glucose import
2.52 4.36e-02 GO:0030334 regulation of cell migration

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.39 8.20e-14 GO:0005737 cytoplasm
2.50 6.58e-12 GO:0044421 extracellular region part
1.47 5.16e-11 GO:0044444 cytoplasmic part
2.45 3.98e-08 GO:0005615 extracellular space
1.84 4.34e-08 GO:0005576 extracellular region
2.05 1.12e-07 GO:0000267 cell fraction
1.22 1.59e-07 GO:0005622 intracellular
1.22 3.54e-07 GO:0044424 intracellular part
3.21 1.76e-06 GO:0005578 proteinaceous extracellular matrix
3.00 3.38e-06 GO:0031012 extracellular matrix
2.41 6.69e-06 GO:0043005 neuron projection
2.05 1.23e-05 GO:0005626 insoluble fraction
1.12 2.60e-05 GO:0005623 cell
1.12 2.60e-05 GO:0044464 cell part
1.90 5.24e-05 GO:0042995 cell projection
1.90 9.44e-05 GO:0005783 endoplasmic reticulum
1.97 1.39e-04 GO:0005624 membrane fraction
4.93 2.10e-04 GO:0005604 basement membrane
2.60 2.41e-04 GO:0005625 soluble fraction
1.60 6.15e-04 GO:0044459 plasma membrane part
2.70 8.29e-04 GO:0030425 dendrite
3.90 8.92e-04 GO:0044420 extracellular matrix part
1.38 1.04e-03 GO:0071944 cell periphery
1.37 1.71e-03 GO:0005886 plasma membrane
2.22 1.98e-03 GO:0009986 cell surface
1.18 3.52e-03 GO:0043226 organelle
2.49 5.45e-03 GO:0048471 perinuclear region of cytoplasm
1.17 7.08e-03 GO:0043229 intracellular organelle
11.87 9.16e-03 GO:0042589 zymogen granule membrane
2.36 1.33e-02 GO:0042598 vesicular fraction
4.18 1.57e-02 GO:0044309 neuron spine
2.33 2.29e-02 GO:0005792 microsome
1.17 4.14e-02 GO:0016020 membrane
12.67 4.46e-02 GO:0043256 laminin complex
21.37 4.55e-02 GO:0005610 laminin-5 complex
4.42 4.73e-02 GO:0005901 caveola

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.23 1.12e-07 GO:0005488 binding
1.38 5.23e-07 GO:0005515 protein binding
1.38 5.39e-03 GO:0046872 metal ion binding
1.36 8.17e-03 GO:0043167 ion binding
1.36 1.01e-02 GO:0043169 cation binding
3.50 1.05e-02 GO:0046906 tetrapyrrole binding
3.47 2.18e-02 GO:0020037 heme binding
3.53 3.36e-02 GO:0019838 growth factor binding
7.77 3.62e-02 GO:0005520 insulin-like growth factor binding
4.84 3.65e-02 GO:0016247 channel regulator activity